Additional notes (click to expand)

Medicinal

Prescription only medicine: Hydrangine-methaqualone

Beta-dichroine a quinazolinone also called febrifugine from the leaves of hydrangeas is 64-100 times more potent than quinine as an antimalarial in animals, but extremely toxic. A synthesised tolyl derivative, methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone), was found to be a mild hypnotic, and marketed in the sleeping tablet, Mandrax. Widely abused and quickly banned by most countries. Illegal manufacture continues and in South Africa methaqualone is the commonest drug of abuse, mixed with cannabis and smoked.
Oakeley, Dr. Henry F. (2013). Wellcome Library notes. link

Other use

Hydrangea blooms are sometimes smoked to induce a hallucinogenic and euphoria inducing effect, a cheaper alternative to cannabis.
The Week, 15 Feb 2014

Beta-dichroine a quinazolinone also called febrifugine from the leaves of hydrangeas is 64-100 times more potent than quinine as an antimalarial in animals, but extremely toxic. A synthesised tolyl derivative, methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone), was found to be a mild hypnotic, and marketed in the sleeping tablet, Mandrax. Widely abused and quickly banned by most countries. Illegal manufacture continues and in South Africa methaqualone is the commonest drug of abuse, mixed with cannabis and smoked.
Oakeley, Dr. Henry F. (2013). Wellcome Library notes. link

Toxicity

Toxic due to cyanogenic glycosides.
Professor Anthony Dayan, 2022

Hydrangea paniculata Siebold 'Phantom'

Family: HYDRANGEACEAE
Genus: Hydrangea
Species: paniculata Siebold
Cultivar: 'Phantom'
Common names: Paniculate hydrangea 'Phantom'
Distribution summary: Japan
Habit: Shrub
Hardiness: H5 - Hardy; cold winter
Garden status: Currently grown
Garden location: Far East (L)
Flowering months: July, August
Reason for growing: Medicinal, toxic, prescription only medicine


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